Dupa cum mentionam intr-un articol precedent, in Octombrie 2017 castigam un premiu (Premiul I) pentru lucrarea „Utilizarea microscopiei confocale in vivo in determinarea preoperatorie a subtipurilor histopatologice de carcinom bazocelular” prezentata in cadrul Congresului National de Dermatologie (organizat de catre Societatea Romana de Dermatologie) desfasurat la Brasov.
Chiar daca studiul prezentat in lucrarea poster a fost doar un studiu pilot realizat pe un numar redus de pacienti, rezultatele acestuia demonstreaza validitatea teoriei initiale: subtipurile histopatologice ale carcinomului bazocelular pot fi distinse inainte ca pacientul sa paseasca in blocul operator, prin tehnici imagistice neinvazive: dermatoscopie si microscopie confocala de reflectanta.
Din abstract:
In vivo confocal reflectance microscopy (RCM) is a relatively new, non-invasive, imaging technique capable of quickly delivering high-quality horizontal optical sections through the skin, with image resolutions close to those of conventional histology slides. This case series includes 4 non-consecutive patients with a total of 6 tumors. The evaluation protocol included clinical examination, dermoscopy, RCM examination, and excisional biopsy of the lesions followed by histopathology examination.
Our results show that the presence of tumoral aggregates as cords connected to the epidermis are suggestive for the diagnosis of superficial BCC. In nodular BCC we have encountered mostly large tumoral islands and tumoral cords. As a distinctive RCM element in infiltrative BCC cases we noted the presence of intradermal hyporefractile areas surrounded by hyperrefractile dense collagen bundles.
In conclusion, a good correlation between the structures observed through RCM and those present on histopathological examination was observed. The corroboration of keratinocyte architecture observed through RCM and dermoscopic criteria allowed for the distinction between histopathological BCC subtypes suggesting that this type of complementary approach could significantly improve the precision of the pre-therapeutic diagnosis, thus lowering the need for invasive diagnostic procedures.
Vreau sa multumesc tuturor celor care, direct sau indirect, au contribuit la realizarea demersului stiintific care a condus la obtinerea acestui premiu.
Intre timp SRD a expediat si diploma/dovada aferenta acestui premiu:
De asemenea, lucrarea s-a materializat si intr-un articol stiintific in cadrul revistei Dermatovenerologia, revista indexata BDI. Articolul il puteti accesa si descarca in mod gratuit vizitand site-ul revistei la: